Cyclobenzaprine: What Is It? Side Effects & Interactions Cleveland Clinic


Cyclobenzaprine: What Is It? Side Effects & Interactions Cleveland Clinic

Recent evidence showed similar effectiveness at half of its manufacturer recommended dose (5 mg), but with fewer adverse effects.33 It may optimally be used in younger patients with limited or no medical conditions. Higher doses of cyclobenzaprine or tizanidine would be appropriate to promote sedation in cases of more severe discomfort or perceived muscular spasm. Although there appears to be insufficient data on metaxalone and methocarbamol, these may be useful in patients who cannot tolerate the sedative properties of cyclobenzaprine or tizanidine. Of note, methocarbamol costs substantially less than metaxalone.

It blocks the pathways of neurotransmitters that signal pain and diminishes the sensations of pain. It is also much more addictive than conventional painkillers or Over-the-counter (OTC) Non-Steroidal Anti-inflammatory Drugs (NSAIDs) available in the market that are pain relievers in action. While the addictiveness of cyclobenzaprine is being debated, anyone exhibiting problematic patterns of substance use can benefit from addiction treatment. This is especially true if someone has been engaging in polydrug use with cyclobenzaprine and other substances. However, the half-life of immediate-release cyclobenzaprine is 18 hours on average, with a range of 8-37 hours.

People might also use Flexeril as a way to come down from Stimulant drugs, such as Cocaine or Adderall. When people addicted to Flexeril attempt to stop taking it or reduce their doses they may start to experience withdrawal symptoms, although these are typically not severe. Flexeril withdrawal symptoms can include headache, nausea, fatigue, and cravings for the drug. Flexeril is the brand name for Cyclobenzaprine, a prescription muscle relaxer that is similar to a class of Antidepressant drugs called Tricyclic Antidepressants. The generic form was first approved in 1977 and is sold in both immediate and extended release versions. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur.

  • It includes meth, opiate, THC, Benzodiazepine, and cocaine.
  • An overlay of cyclobenzaprine with a member of each is at right.
  • There are options available across the full continuum of care to help with substance abuse.
  • Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur.
  • Although rare, deaths may occur from overdosage with FLEXERIL.
  • Studies have compared cyclobenzaprine, methocarbamol, and other skeletal muscle relaxants and found that they are equally effective in treating acute musculoskeletal conditions.

Regardless of the slight high, it gives to users, there is also the potential of becoming dependent on it. The slight relaxing feeling can become something that becomes a normal part of their everyday experience. When a patient becomes physically dependent on Flexeril, they’re often at a much higher risk of developing a cyclobenzaprine addiction further down the line. This addiction is marked by compulsive drug-seeking behaviors, even when the negative effects of these behaviors are fully recognized.

Cyclobenzaprine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

Cyclobenzaprine oral tablet may cause drowsiness and dizziness. This is more likely to happen in the few hours after you take it. The animal use protocol was approved by the Mercer University Institutional Animal Care and Use Committee. Animals had free access to commercial food pellet and fresh tap water.

Cyclobenzaprine: Side Effects, dosage, uses, and more – Medical News Today

Cyclobenzaprine: Side Effects, dosage, uses, and more.

Posted: Fri, 22 May 2020 13:31:24 GMT [source]

The following list of adverse reactions is based on the experience in 473 patients treated with FLEXERIL 10 mg in additional controlled clinical studies, 7607 patients in the post-marketing surveillance program, and reports received since the drug was marketed. The overall incidence of adverse reactions among patients in the surveillance program was less than the incidence in the controlled clinical studies. Flexeril is used together with rest and physical therapy to treat skeletal muscle conditions such as pain, injury, or spasms. Sometimes people will even have a heart attack or develop seizures. In order to quit safely, you need to opt for professional Flexeril rehab. Getting treated for your Flexeril addiction professional has so many benefits.

When used alone, alcohol can end up slowing respiration to deadly levels due to alcohol poisoning. Flexeril abuse can also end up leading to dangerously slow respiration. When Flexeril and alcohol are mixed, however, these qualities can actually end up overlapping, making the potentially fatal risk of low respiration even more likely to occur. The alcohol also increases the side effects of cyclobenzaprine. This includes dizziness, difficulty thinking, and drowsiness. As a result, they may be more likely to physically hurt themselves while abusing cyclobenzaprine and alcohol.

Can I take Cyclobenzaprine (Flexeril) if I’m pregnant or breastfeeding?

The problem with combining Flexeril and alcohol comes from the fact that both of these drugs are actually central nervous system (CNS) depressants. That means that both Flexeril and alcohol have a tendency to slow down the body’s natural processes. One of the most important bodily processes that these two drugs can end up impacting is respiration.

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Generic cyclobenzaprine may be under $0.50 for 30 tablets of the 10mg dose through the BuzzRx discount program. Also, methocarbamol and cyclobenzaprine are not recommended in pregnant women, elderly adults, and young children. As with all medications, the costs of cyclobenzaprine can vary. Cyclobenzaprine oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

What should I know about storage and disposal of this medication?

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which flexeril online you are using the medicine. The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine.


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